Portfolio by

Design

Portfolio by Design

Lumira invests in companies developing innovative biotherapeutics, medical technologies and consumer health solutions. We are proud to have partnered with so many successful companies and management teams that have brought dozens of new products to patients, and by so doing have helped us generate industry-leading financial returns for our investors.

AmacaThera

AmacaThera is developing a unique, injectable hydrogel platform technology for a wide range of medical applications. It’s first product aims to reduce the need for opioids and provide sustained relief for post-operative pain.

Antiva Biosciences

Antiva Biosciences is a clinical-stage biopharmaceutical company developing novel, topical therapeutics for the treatment of diseases caused by HPV infection.

Arclight Therapeutics

Arclight Therapeutics is building a portfolio of neurodegeneration companies to accelerate transformative neuroscience.

BioTheryX

BioTheryX is a clinical-stage company with expertise in Targeted Protein Degradation with their novel, small molecule PHM to restore protein homeostasis and treat a wide range of diseases and serious cancers AML and MDS.

Bright Angel Therapeutics Company Logo

Bright Angel Therapeutics

Bright Angel Therapeutics is a pre-clinical stage biotechnology company focused on the development of novel therapeutics for the treatment of drug-resistant and life-threatening fungal infections.

Cadence Neuroscience

Cadence Neuroscience is developing a fundamentally new approach to neuromodulation with an unprecedented potential to treat many neurological diseases that cannot be adequately addressed with available treatment options.

Cardiac Dimensions

Cardiac Dimensions is developing a minimally invasive implantable product to treat mitral valve regurgitation associated with congestive heart failure.

Congruence Neuroscience

Congruence Therapeutics is a biotechnology company at the interface of computational and experimental drug discovery, designing novel small molecules to treat diseases caused by protein misfolding.

Corvia Medical

Corvia Medical is a private medical device company based in Massachusetts developing a catheter-delivered implant for treating diastolic heart failure.

Cyrano Therapeutics

Cyrano Therapeutics is a private, venture-backed clinical stage regenerative medicine company developing a novel therapy to restore smell and flavor function.

DAMONA Pharmaceuticals

DAMONA is on a mission to develop small molecule therapeutics to improve the lives of patients suffering from cognitive impairment as a result of depression and other diseases of aging.

 

Deka BioSciences

Deka Biosciences is developing novel cytokine therapies to drive cures in cancer patients and control inflammatory diseases

Edesa Biotech

Edesa Biotech is a clinical stage pharmaceutical company that brings innovative new treatments for dermatological and anorectal diseases.

Endogenex

Endogenex is a clinical stage medical device company shifting the treatment paradigm for people living with Type 2 Diabetes by resetting the cellular signaling of the duodenum to help the body better manage blood sugar levels.

Endotronix

Endotronix, a digital health medtech company, is developing an integrated platform to provide comprehensive, reimbursable health management tools for patients suffering from advanced heart failure.

enGene

enGene has a novel proprietary method to deliver therapeutic proteins to the gastrointestinal (GI) tract to treat diseases of the GI tract.

Exact Imaging

Exact Imaging is the world’s leader in high-resolution micro-ultrasound systems enabling real-time imaging and guided biopsies for prostate cancer.

Fusion Pharmaceuticals

Fusion Pharmaceuticals is a clinical-stage bio-pharmaceutical company developing next-generation radio-pharmaceuticals as precision medicines for the treatment of cancer.

G1 Therapeutics

G1 Therapeutics is a clinical-stage pharmaceutical company focused on the discovery and development of novel small-molecule therapies to address significant unmet needs in oncology.

GenEp

GenEp is a biotechnology company developing therapies that address unmet needs in patients with epilepsy.

HistoSonics

HistoSonics is a private medical device company whose mission is to redefine cancer treatment with a non-invasive, highly precise, cost-effective method of tumor destruction call Robotically Assisted Sonic Therapy (RAST™), based on the science of histotripsy.

IMV

IMV is a clinical stage company developing a suite of immunotherapeutics for the treatment of solid tumors and infectious diseases.

Iterion Therapeutics

Iterion Therapeutics is developing novel cancer therapeutics targeting nuclear β-catenin, a historically “undruggable” oncology target implicated in cell proliferation.

KalGene Inc

KalGene Inc is a pre-clinical stage company focussed on the development of precision medicine therapeutics to slow the progression of Alzheimer’s disease.

KisoJi Biotechnology

KisoJi Biotechnology is an early stage biotechnology company engaged in the development of antibodies for the treatment of various cancers.

Medexus Pharmaceuticals

Medexus Pharmaceuticals is a leading specialty pharmaceutical company with a strong North American commercial platform. Medexus is focused on the therapeutic areas of auto-immune disease and pediatrics.

Notch Therapeutics

Notch is an immune cell therapy company developing a next-generation pipeline of off-the-shelf, universally compatible, genetically tailored T cell therapeutics derived from renewable stem cell sources for the treatment of high-impact diseases, with an initial focus on cancer.

PIC Therapeutics

PIC Therapeutics is developing a new generation of therapeutics based on the modulation of RNA translation to improve how we treat cancer.

Specific Biologics

Specific Biologics is an early-stage biotechnology company on a mission to develop novel gene editing technologies to treat diseases through precision gene editing

Thryv Therapeutics

Thryv Therapeutics is developing therapies for genetic heart diseases pioneering a precision medicine approach to treat patients with Long QT Syndrome and potentially other arrhythmias.

Transposon Therapeutics

Transposon Therapeutics is a clinical-stage company specializing in the development of therapeutics for neurodegenerative diseases.

XyloCor Therapeutics

XyloCor Therapeutics is a biopharmaceutical company focused on the development of novel gene therapy for unmet needs in advanced coronary artery disease.

X4 Pharmaceuticals

X4 Pharmaceuticals, Inc is a leader in the discovery and development of novel CXCR4-targeted small molecule therapeutics to benefit people with rare immune system disorders.

Aurinia Pharmaceuticals

Aurinia Pharmaceuticals lead drug, LUPKYNIS (voclosporin), was approved in January 2021 as the first oral therapy for lupus nephritis, a condition that causes irreversible kidney damage and increases the risk of kidney failure, cardiac events, and death

Bardy Diagnostics

Bardy Diagnostics, an  innovator in digital health and remote patient monitoring, with a focus on providing the most diagnostically-accurate and patient-friendly cardiac patch and other monitors to the industry was acquired by Hillrom for $375 million in January 2021

Engage Therapeutics

Engage Therapeutics is focused on epilepsy patients suffering from uncontrolled seizures with what could be the first rescue treatment with the potential to stop their seizures. The company was acquired by UBC for up to US$270 million in June 2020.

 

ESSA Pharma

Essa Pharmaceuticals is a clinical stage company developing a small molecule therapy to overcome the issue of drug resistance for patients with prostate cancer.

Forbius

Forbius is a clinical stage company that designs and develops biotherapeutics for treatment of cancer and fibrosis. The company was acquired by Bristol Myers Squibb in August 2020.

MAKO Surgical Corp.

Lumira was an early investor in MAKO Surgical Corp. prior to its IPO and later when it was acquired by Stryker for $1.65 billion in 2013 for its minimally invasive robotic surgical arm for partial knee and total hip arthroplasty.

OpSens

Opsens is a fiber optic sensors manufacturer offering solutions for interventional cardiology Fractional Flow Reserve (FFR) as well as solutions for oil and gas industrial applications.

Pharmasset

Pharmasset was acquired by Gilead in 2011 for $11 billion for their oral therapeutics for the treatment of hepatitis C virus (HCV) and human immunodeficiency virus (HIV).

Zymeworks

Zymeworks is a biotherapeutics company that is developing best-in-class Azymetric™ bi-specific antibodies and antibody drug conjugates for the treatment of cancer, autoimmune and inflammatory diseases.

Alveolus

Alveolus, developer of next generation non-vascular interventional stent technology for use in the lungs, was acquired by Merit Medical Systems Inc. in February 2008.

Ception Therapeutics

Ception Therapeutics was acquired by Cephalon Inc. in March 2010 in a deal worth $350 million plus significant future millstones. Cephalon Inc. was subsequently acquired by Teva in 2011.

Corus Pharmaceuticals

Corus Pharmaceuticals, developer of Aztreonam for treatment of cystic fibrosis and Lidocaine for treatment of oral corticosteroid dependent asthma, was acquired by Gilead in August 2006 for $365 million.

Depomed

Lumira Ventures led a PIPE in Depomed in 2003 and fully exited in 2006 after the FDA approved the company’s two lead products in 2005.

Guava Technologies

Guava Technologies was acquired by Millipore Inc. in February 2009.

ISTA Pharmaceuticals

From the time we invested in 2002 to our exit in 2006, ISTA Pharmaceuticals launched 3 products in the United States to treat diseases of the eye.

KAI Pharmaceuticals

KAI Pharmaceuticals Inc., developer of novel therapeutics for kidney disease, was acquired by Amgen in 2012 for US$315 million.

Morphotek

Morphotek was acquired by Eisai Inc. in April 2007 for $325 million.

Resonant Medical

Resonant Medical, developer of 3D ultrasound image-guided radiotherapy products, was acquired by Elekta in May of 2010.

Spinal Kinetics

Spinal Kinetics, developer of artificial discs for degenerative diseases of the spine, was acquired by Orthofix  in March 2018.

Think Research

Think Research develops knowledge-based and leading clinical content tools that empower clinicians to deliver the best evidence-based care to patients and drive better patient outcomes.

U-Systems

Automated Breast Ultrasound company, U-Systems, was acquired by GE Healthcare Limited in November 2012.